Running the ABS - Anti-Lock Brake System (ABS) Module Configuration acts as a factory reset. Since you are connected live, it will ping Ford's servers and reload the factory As-Built data into the module. This is generally safe to execute, but it will wipe all current learned values. If you run this configuration, you must re-run the IVD Initialization Sequence immediately afterward to establish a new baseline.
Before rewriting the ABS module, verify two things:
Mechanical Alignment (Drag Link): Super Duties use a solid front axle. To properly center the steering wheel, the alignment technician must adjust the drag link sleeve. If they incorrectly adjusted the tie rod ends instead to make the truck track straight, the steering gear (pinion) will be mechanically out of phase with the steering column sensor. This creates a physical degree mismatch that software cannot fix.
Self-Learning Drive Cycle: On 2023+ ETO steering systems, the angle sensor often calibrates dynamically. Take the truck for a drive on a straight, flat road above 20 mph for a mile or two to see if the system zeroes out the 21.6-degree offset on its own.
If you confirm the drag link was adjusted correctly and a drive cycle fails to clear the offset, proceed with the ABS Module Configuration followed by a fresh IVD reset.