Yes, the portable toilets and cassette toilets can have an interesting effect if sealed shut, then driven to high elevation and not vented to adjust internal pressure before being used. Ha. Most only do it once!
For us, the happy in-between toilet is a separating toilet. They are not full on "composting" toilet, which are larger, have crank and vent, etc. but the important part is separating the liquids and solids. Something like the Trelino toilets. The downfall of portable toilets is they mix solids and liquids and that is what makes sewage. Horrid stuff. Keep the liquids and solids separate makes a huge different.
We've not used the Trelino yet because we purchased on black friday (that could be worked into a pun or joke. Ha), but in principle, we have already experimented with this concept by moving away from our portable toilet last year and going to separate liquids container and a solids "bucket" type container. The experiment was a success hence the purchase of the Trelino Evo M. But one can do a home made setup on the cheap or even cheaper is a homemade "bagging" toilet where it all goes in the same lined container and is changed after nearly every use (similar to Wrappon but costs $5 rather than $1,500. You can buy a lot of biodegradeable liner bags for that. You just don't get the electric sealing feature and bag replacement is a bit more hands on).
If we are dispersed camping (which is 95% of the time), it is allowed, and environment isn't prohibitive (biting insects, cold temps), we'll continue to dig and use cat holes for solids (and pack out paper rather than burying it). In the 5% of the time we camp in a campground (have fishing boat in tow, for example, so can't bounce up a forest service road), we'll use facilities there if they are not nasty. In any case, the indoor toilet use won't be used for solids every day nor every outing, but it's nice to have the option. We'll use the Trelino for liquids every day/night. Trelino is light and portable enough that we'll be able to easily move it from the camper into our little hub screenhouse if it's a matter of bugs being an issue.
Besides not creating sewage (mixed liquids and solids), the other benefit of a separating toilet (or bagging toilet, like the Wrappon, for that matter) is not using water to flush. Between flushing and dumping rinsing, a portable toilet and cassette toilet use up a lot of precious water.